CBD Oil and Cannabinoid Receptors

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For years now, the demand for CBD oil has increased among both patients who need medical alternatives and recreational activities. Research has extensively proven that compounds found in the cannabis plant have a wide variety of effect and medicinal functions on us. Phytocannabinoids have been the subject of scrutiny for quite some time now. The effects of the compounds are visible and undeniable. Some scientists found that the brain naturally produces phytocannabinoids, which are referred to as endogenous cannabinoids. There is, therefore, a significant relationship between the natural receptors and consumed phyto-cannabinoids.

Overview

Cannabinoid receptors are all over your body to connect each part of your body to the brain. They are located throughout the body to bide the sites and promote better physiological functions of the muscular system among others. Other dependent systems include the immune, and digestive, and nervous system. The main receptors are; cannabinoid-receptor type 1 (CB1) and type 2 (CB2)

Type 1(CB1) are G protein-coupled receptors, which respond to endogenous cannabinoids. They are found mainly in the central nervous system as well as some of the peripheral tissues in minimal numbers. Some of the tissues are the heart, spleen, endocrine glands, and other main organs. Apart from CBD, the receptor responds to THC and other phytocannabinoids as well.

CB2 is located only in peripheral tissues unlike CB1, which is found in the central nervous system too. It also contains G protein and responds to endogenous cannabinoids, and phyto-cannabinoids as well.

How they Function

Both G protein receptors are tasked with regulating the level of neuro-hormones in your body. They play an active role in many different physiological processes such as mood, memory, chronic pain, and regulating appetite. When they are introduced to receptors, they respond and produce desired changes.

The consequences in Medicine

The studies on direct effects of various phyto-cannabinoids of the body persist to date. Scientists have established that there are specific cannabinoids, which bind directly with specific receptors. For example, when exposed to THC, CB1 shows a significant reaction. Cannabidiol, however, does not show much a reaction or readiness to bind with either CB1 or CB2 receptors. It instead stimulates both of them and can only be limited by CBD. This means a reduction of the unwanted side effects of consuming high amounts of THC.

The receptors are responsible for maintaining a balance of daily functions in the body. On the other hand, these receptors are activated when cannabinoids get introduced into the body especially from external sources. Since it is part of the endocannabinoid system, the receptor regulates most functions. It is, therefore, logical that the entire system can be balanced enough to alleviate specific symptoms. This means that many medical issues can be treated easily. A wide variety of conditions such as osteoporosis, Parkinson’s disease, glaucoma, hypertension, and related medical challenges. Other issues include but not limited to seizures, movement disorders, obesity, myocardial infarction, anxiety, and many more.

Effect of CBD on the Endocannabinoid system

The key role of the endocannabinoid system is to produce cannabinoids within the body. Researchers have discovered that the system also responds to cannabinoids from external sources. Introduction of external cannabinoids such as CBD helps to manipulate the endocannabinoid system. According to the National Institute of Health, this is a crucial part of the treatment of a variety of ailments. Some of the most common include;

  • Acne

  • ADHD

  • Amyotrophic Lateral Sclerosis (ALS)

  • Anxiety

  • Bacterial Infections

  • Broken Bones

  • Depression

  • Diabetes

  • Dyskinesia

  • Epilepsy

  • Heart Disease

  • Inflammation

  • Irritable Bowel Syndrome 

  • Mad Cow Disease

  • Multiple Sclerosis (MS)

  • Nausea

  • Pain

  • Parkinson’s

  • Psoriasis

  • Rheumatoid Arthritis

  • Schizophrenia

  • Substance Abuse/Withdrawal

  • And More!

Conclusion

CBD’s role in the body is undeniably significant. Research has extensively proven that compounds found in the cannabis plant has a wide variety of effect and medicinal functions. Phytocannabinoids have been the subject of scrutiny for quite some time now. The effects of the compounds are visible and undeniable. Some scientists found that the brain naturally produces phytocannabinoids, which are referred to as endogenous cannabinoids. There is, therefore, a significant relationship between the natural receptors and consumed phyto-cannabinoids.

Alex Mihailov